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Bock PJ, no protrusion II Protrusion, spontaneous reduction III Protrusion, manual reduction IV Chronic protrusion Dietary modification Office procedure Dietary modification Office procedure Office procedure Excisional hemorrhoidectomy Excisional hemorrhoidectomy 12 Gardner-Medwin Advances of the past 13 yr, since the discovery of dystrophin by means of reverse genetics, have been so fundamental that it is now a truism to regard the classification and genetic diagnosis of the MDs as firmly based on molecular biology.

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